Iba1 antibody
GTX100042
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetAIF1
Overview
- SupplierGeneTex
- Product NameIba1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID199
- Target nameAIF1
- Target descriptionallograft inflammatory factor 1
- Target synonymsAIF-1; allograft inflammatory factor 1; IBA1; interferon gamma responsive transcript; ionized calcium-binding adapter molecule 1; IRT1; IRT-1; protein G1
- HostRabbit
- IsotypeIgG
- Protein IDP55008
- Protein NameAllograft inflammatory factor 1
- Scientific DescriptionThis gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Calcium-dependent cytosolic phospholipase A(2) activation is implicated in neuroinflammation and oxidative stress associated with ApoE4. Wang S et al., 2022 Jun 15, Mol NeurodegenerRead more
- Fecal Microbiota Transplantation Exerts Neuroprotective Effects in a Mouse Spinal Cord Injury Model by Modulating the Microenvironment at the Lesion Site. Jing Y et al., 2022 Jun 29, Microbiol SpectrRead more
- Effects of subchronic dietary exposure to the engineered nanomaterials SiO(2) and CeO(2) in C57BL/6J and 5xFAD Alzheimer model mice. Sofranko A et al., 2022 Mar 25, Part Fibre ToxicolRead more
- Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration. Amamoto R et al., 2022 Mar 22, ElifeRead more
- TNFalpha-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation. Huang WY et al., 2022 Feb 2, J NeuroinflammationRead more
- Minimally invasive protocols and quantification for microglia-mediated perineuronal net disassembly in mouse brain. Venturino A et al., 2021 Dec 17, STAR ProtocRead more
- Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinsons disease. Lin YE et al., 2021 Nov 15, ElifeRead more
- Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor degenerative environment. Maes ME et al., 2021 Dec 10, Mol Ther Methods Clin DevRead more
- Spatiotemporal characterisation of ischaemic lesions in transient stroke animal models using diffusion free water elimination and mapping MRI with echo time dependence. Farrher E et al., 2021 Dec 1, NeuroimageRead more