IDH889 [1429179-07-6]

TargetMol Chemicals

IDH889 [1429179-07-6]

9

1429179-07-6

Chemical

Research Use Only

IDH889

C23H25FN6O2

436.48

IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 microM, 0.072 microM, and 1.38 microM for IDH1R132H, IDH1R132C, and IDH1wt).

3 years

CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ncc(cn2)-c2ccc(F)c(C)c2)n1

-20°C

12352200