IDH889
M11277
CAS Number1429179-07-6
Product group Chemicals
Molecular Weight436.48
Overview
- SupplierAbMole BioScience
- Product NameIDH889
- Delivery Days Customer9
- CAS Number1429179-07-6
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC23H25FN6O2
- Molecular Weight436.48
- Scientific DescriptionIDH889 is an orally available, brain permeable, allosteric and mutation-specific inhibitor of isocitrate dehydrogenase (IDH1). IDH889 showed high selectivity against IDH1R132 * mutant, with IC50 values of 0.02 uM, 0.072 uM and 1.38 uM against IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 showed high inhibition of intracellular 2-Hg level with IC50 value of 0.014 uM.
- UNSPSC12352200