Bio-Connect

IDH889

M11277
AbMole BioScience
CAS Number1429179-07-6
Product group Chemicals
Molecular Weight436.48
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    IDH889
  • Delivery Days Customer
    9
  • CAS Number
    1429179-07-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C23H25FN6O2
  • Molecular Weight
    436.48
  • Scientific Description
    IDH889 is an orally available, brain permeable, allosteric and mutation-specific inhibitor of isocitrate dehydrogenase (IDH1). IDH889 showed high selectivity against IDH1R132 * mutant, with IC50 values of 0.02 uM, 0.072 uM and 1.38 uM against IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 showed high inhibition of intracellular 2-Hg level with IC50 value of 0.014 uM.
  • UNSPSC
    12352200