The data was published in the journal Front Immunol in 2019. PMID: 31681271
The data was published in the journal Front Immunol in 2019. PMID: 31681271
IDO1 antibody [10.1]
GTX54075
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
TargetIDO1
Overview
- SupplierGeneTex
- Product NameIDO1 antibody [10.1]
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10.1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3620
- Target nameIDO1
- Target descriptionindoleamine 2,3-dioxygenase 1
- Target synonymsIDO; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine 2,3-dioxygenase 1; indoleamine-pyrrole 2,3-dioxygenase
- HostMouse
- IsotypeIgG3
- Protein IDP14902
- Protein NameIndoleamine 2,3-dioxygenase 1
- Scientific DescriptionThis gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Switch of NAD Salvage to de novo Biosynthesis Sustains SIRT1-RelB-Dependent Inflammatory Tolerance. Zhang J et al., 2019, Front ImmunolRead more
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