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iFSP1 [150651-39-1]

iFSP1 [150651-39-1]

Research Use Only
T11631
TargetMol Chemicals
CAS Number150651-39-1
DownloadMSDS
Product group Chemicals
Estimated Purity98.74%
Molecular Weight323.35
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    iFSP1 [150651-39-1]
  • Delivery Days Customer
    4
  • CAS Number
    150651-39-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    iFSP1
  • Estimated Purity
    98.74%
  • Molecular Formula
    C20H13N5
  • Molecular Weight
    323.35
  • Scientific Description
    iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R)-RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1ccc(cc1)-c1c(C#N)c(N)n2c3ccccc3nc2c1C#N
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • FSP1 is a glutathione-independent ferroptosis suppressor. Doll S et al., 2019 Nov, Nature
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