iFSP1

AbMole BioScience

iFSP1

9

150651-39-1

Chemical

Research Use Only

C20H13N5

323.35

IFSP1 is an effective, selective and glutathione-independent inhibitor of ferroptosis Suppressor protein 1 (FSP1/AIFM2) with an EC50 value of 103 nM. IFSP1 can selectively induce iron death in Pfa1 cells and HT1080 cells with GPX4 knockout gene overexpressing FSP1.

CC1=CC=C(C=C1)C2=C(C#N)C3=NC4=C(C=CC=C4)[N]3C(=C2C#N)N

12352200