IGF1R beta antibody [HL1957] detects IGF1R beta protein at cell membrane by immunofluorescent analysis. Sample: MCF-7 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: IGF1R beta stained by IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. Blue: Fluoroshield with DAPI (GTX30920). Scale bar= 10μm.
![Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637794/GTX637794_45012_20230421_WB_TPM_watermark_23050223_612.webp "Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.")
![Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637794/GTX637794_T-44851_20230428_WB_M_23050223_578.webp "Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![Wild-type (WT) and IGF1R knockout (KO) HeLa cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637794/GTX637794_45012_20230602_WB_KO_watermark_23060622_722.webp "Wild-type (WT) and IGF1R knockout (KO) HeLa cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.")
![Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637794/GTX637794_45012_20230811_WB_R_23081619_113.webp "Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![IGF1R beta antibody [HL1957] detects IGF1R protein at cell membrane and cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. IGF1R beta stained by IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX637794/GTX637794_45012_20230822_IHC-P_23090619_602.webp "IGF1R beta antibody [HL1957] detects IGF1R protein at cell membrane and cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. IGF1R beta stained by IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
IGF1R beta antibody [HL1957] detects IGF1R beta protein at cell membrane by immunofluorescent analysis. Sample: MCF-7 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: IGF1R beta stained by IGF1R beta antibody [HL1957] (GTX637794) diluted at 1:1000. Blue: Fluoroshield with DAPI (GTX30920). Scale bar= 10μm.
IGF1R beta antibody [HL1957]
GTX637794
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIGF1R
Overview
- SupplierGeneTex
- Product NameIGF1R beta antibody [HL1957]
- Delivery Days Customer9
- Application Supplier NoteICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL1957
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID3480
- Target nameIGF1R
- Target descriptioninsulin like growth factor 1 receptor
- Target synonymsCD221, IGFIR, IGFR, JTK13, insulin-like growth factor 1 receptor, IGF-I receptor
- HostRabbit
- IsotypeIgG
- Protein IDP08069
- Protein NameInsulin-like growth factor 1 receptor
- Scientific DescriptionThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
Datasheet
Related products
Product group Antibodies
Anti-IGF-1 [7973 [M23]], Mouse IgG1, kappaAB04263-1.1
ApplicationsWestern Blot, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetIGF1R
- SizePrice
Product group Antibodies
Anti-IGF1R Antibody Picoband(r)A00070-3-CARRIER-FREE
ApplicationsWestern Blot, ELISA
ReactivityHuman
TargetIGF1R
- SizePrice
Product group Antibodies
Anti-IGF1R Antibody144-62454
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetIGF1R
- SizePrice
Product group Antibodies
Igf1R Polyclonal AntibodyCAC10405
ApplicationsImmunoFluorescence, ELISA
TargetIGF1R
- SizePrice
Product group Antibodies
References
IGF1R Polyclonal AntibodyBS-0227R
ApplicationsFlow Cytometry
ReactivityBovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep
TargetIGF1R
- SizePrice
Product group Antibodies
IGF1R/INSR AntibodyCSB-PA003003
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetIGF1R
- SizePrice
Product group Antibodies
IGF1R alpha + beta antibodyGTX10729
ApplicationsWestern Blot, ELISA, Neutralisation/Blocking
ReactivityHuman
TargetIGF1R
- SizePrice
![IHC-P analysis of human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F) using GTX83067 IGF1R beta antibody [3C8B1].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83067/GTX83067_20170912_IHC-P_w_23061322_458.webp)
Product group Antibodies
IGF1R beta antibody [3C8B1]GTX83067
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
ReactivityHuman
TargetIGF1R
- SizePrice