IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody
GTX133450
ApplicationsWestern Blot
Product group Antibodies
TargetIGF1R
Overview
- SupplierGeneTex
- Product NameIGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID3480
- Target nameIGF1R
- Target descriptioninsulin like growth factor 1 receptor
- Target synonymsCD221, IGFIR, IGFR, JTK13, insulin-like growth factor 1 receptor, IGF-I receptor
- HostRabbit
- IsotypeIgG
- Protein IDP08069
- Protein NameInsulin-like growth factor 1 receptor
- Scientific DescriptionThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer and overcoming drug resistance.Read more

