IGF1R beta (phospho Tyr950) antibody

GeneTex

IGF1R (phospho Tyr950) antibody

9

The full-length IGF1R includes the 30 aa signal peptide that is cleaved during maturation. The Tyr950 of mature IGF1R is equivalent to Tyr980 of uncleaved IGF1R.

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.44 mg/ml

Unconjugated

IGF1R

insulin like growth factor 1 receptor

CD221; IGF-I receptor; IGFIR; IGFR; insulin-like growth factor 1 receptor; JTK13; soluble IGF1R variant 1; soluble IGF1R variant 2

Rabbit

IgG

Insulin-like growth factor 1 receptor

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203