IGF2R antibody [MEM-238] (Biotin)

GeneTex

IGF2R antibody [MEM-238] (Biotin)

9

Flow Cytometry, ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

MEM-238

1 mg/ml

Biotin

IGF2R

insulin like growth factor 2 receptor

CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR 300, MPR1, MPR300, MPRI, cation-independent mannose-6-phosphate receptor, 300 kDa mannose 6-phosphate receptor, CI Man-6-P receptor, IGF-II receptor, M6P/IGF2 receptor, insulin-like growth factor II receptor

Mouse

IgG1

Cation-independent mannose-6-phosphate receptor

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

Human, Primate

2°C to 8°C

41116161