IGFBP3 antibody [N2C3]
GTX100454
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIGFBP3
Overview
- SupplierGeneTex
- Product NameIGFBP3 antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.31 mg/ml
- ConjugateUnconjugated
- Gene ID3486
- Target nameIGFBP3
- Target descriptioninsulin like growth factor binding protein 3
- Target synonymsacid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP-53; growth hormone-dependent binding protein; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; insulin-like growth factor-binding protein 3
- HostRabbit
- IsotypeIgG
- Protein IDP17936
- Protein NameInsulin-like growth factor-binding protein 3
- Scientific DescriptionThis gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Differential expression of hypoxia-inducible factors related to the invasiveness of epithelial ovarian cancer. Shih HJ et al., 2021 Nov 25, Sci RepRead more
- IGFBP3 inhibits angiogenesis through intracellular regulation of THBS1 expression. Shih HJ et al., 2020, Am J Cancer ResRead more
- Exosomes derived from induced vascular progenitor cells promote angiogenesis in vitro and in an in vivo rat hindlimb ischemia model. Johnson TK et al., 2019 Oct 1, Am J Physiol Heart Circ PhysiolRead more
- Targeting insulin-like growth factor-binding protein-3 by microRNA-125b promotes tumor invasion and poor outcomes in non-small-cell lung cancer. Wang HH et al., 2017 Apr, Tumour BiolRead more