IGLL1 Polyclonal Antibody
RD219173A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetIGLL1
Overview
- SupplierReddot Biotech
- Product NameIGLL1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.14 mg/ml
- ConjugateUnconjugated
- Gene ID3543
- Target nameIGLL1
- Target descriptionimmunoglobulin lambda like polypeptide 1
- Target synonyms14.1; AGM2; CD179 antigen-like family member B; CD179b; CD179b antigen; ig lambda-5; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; immunoglobulin lambda-like polypeptide 1; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; immunoglobulin-related protein 14.1; lambda5; Pre-B lymphocyte-specific protein-2; VPREB2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.IGLL1 (Immunoglobulin Lambda Like Polypeptide 1) is a Protein Coding gene. Diseases associated with IGLL1 include Agammaglobulinemia 2 and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Cell surface interactions at the vascular wall and Primary immunodeficiency. An important paralog of this gene is IGLL5.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203