IL1 beta antibody [S1H12]

GeneTex

IL1 beta antibody [S1H12]

9

Does not show any cross reaction with recombinant human IL-1α, recombinant murine IL-1α or IL-1β.

ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.02 - 0.1 microg/ml. Predicted molecular weight: 30 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot, ELISA

Research Use Only

Monoclonal

S1H12

1 mg/ml

Unconjugated

Liquid

IL1B

interleukin 1 beta

catabolin; IL-1; IL-1 beta; IL1beta; IL1-BETA; IL1F2; interleukin 1beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta

Mouse

IgG1

Interleukin-1 beta

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203