IL1 Receptor 2 antibody, Internal
GTX88100
Overview
- SupplierGeneTex
- Product NameIL1 Receptor 2 antibody, Internal
- Delivery Days Customer7
- Antibody SpecificityThis antibody is expected to cross-react with both reported isoforms (NP_004624.1; NP_001248348.1).
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID7850
- Target nameIL1R2
- Target descriptioninterleukin 1 receptor type 2
- Target synonymsantigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 type II receptor; IL-1R-2; IL1R2c; IL1RB; IL-1R-beta; IL-1RT2; IL-1RT-2; interleukin 1 receptor type II variant 3; interleukin-1 receptor beta; interleukin-1 receptor type 2; interleukin-1 receptor type II; type II interleukin-1 receptor, beta
- HostGoat
- IsotypeIgG
- Protein IDP27930
- Protein NameInterleukin-1 receptor type 2
- Scientific DescriptionThe protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis. Mar AC et al., 2015 Sep 4, J Biol ChemRead more