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IL1 Receptor 2 antibody [N3C3]

Research Use Only
GTX108702
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIL1R2
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL1 Receptor 2 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7850
  • Target name
    IL1R2
  • Target description
    interleukin 1 receptor type 2
  • Target synonyms
    antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 type II receptor; IL-1R-2; IL1R2c; IL1RB; IL-1R-beta; IL-1RT2; IL-1RT-2; interleukin 1 receptor type II variant 3; interleukin-1 receptor beta; interleukin-1 receptor type 2; interleukin-1 receptor type II; type II interleukin-1 receptor, beta
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP27930
  • Protein Name
    Interleukin-1 receptor type 2
  • Scientific Description
    The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis. Mar AC et al., 2015 Sep 4, J Biol Chem
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