IL1 Receptor 2 antibody [N3C3] detects IL1 Receptor 2 protein at cytoplasm in human colon cancer by immunohistochemical analysis. Sample: Paraffin-embedded human colon cancer. IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
![IL1 Receptor 2 antibody [N3C3] detects IL1 Receptor 2 protein at cytoplasm in human lung cancer by immunohistochemical analysis. Sample: Paraffin-embedded human lung cancer. IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX108702/GTX108702_40016_20150420_IHC_w_23060120_360.webp "IL1 Receptor 2 antibody [N3C3] detects IL1 Receptor 2 protein at cytoplasm in human lung cancer by immunohistochemical analysis. Sample: Paraffin-embedded human lung cancer. IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX108702/GTX108702_40016_20170929_WB_M_R_w_23060120_131.webp "Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![LoVo whole cell and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX108702/GTX108702_40016_20240823_WB_Fraction_24082802_194.webp "LoVo whole cell and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
IL1 Receptor 2 antibody [N3C3] detects IL1 Receptor 2 protein at cytoplasm in human colon cancer by immunohistochemical analysis. Sample: Paraffin-embedded human colon cancer. IL1 Receptor 2 antibody [N3C3] (GTX108702) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
IL1 Receptor 2 antibody [N3C3]
GTX108702
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIL1R2
Overview
- SupplierGeneTex
- Product NameIL1 Receptor 2 antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7850
- Target nameIL1R2
- Target descriptioninterleukin 1 receptor type 2
- Target synonymsCD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, interleukin-1 receptor type 2, CD121 antigen-like family member B, IL-1 type II receptor, IL-1R-beta, antigen CDw121b, interleukin-1 receptor beta, interleukin-1 receptor type II, type II interleukin-1 receptor, beta
- HostRabbit
- IsotypeIgG
- Protein IDP27930
- Protein NameInterleukin-1 receptor type 2
- Scientific DescriptionThe protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mar AC, Chu CH, Lee HJ, et al. Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis. J Biol Chem. 2015,290(36):22212-24. doi: 10.1074/jbc.M115.644823Read this paper
Datasheet
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