
Immunohistochemical analysis of paraffin-embedded PC3 xenograft, using IL1 Receptor antagonist(GTX106490) antibody at 1:500 dilution.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
IL1 Receptor antagonist antibody
GTX106490
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetIL1RN
Overview
- SupplierGeneTex
- Product NameIL1 Receptor antagonist antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.44 mg/ml
- ConjugateUnconjugated
- Gene ID3557
- Target nameIL1RN
- Target descriptioninterleukin 1 receptor antagonist
- Target synonymsCRMO2, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4, interleukin-1 receptor antagonist protein, IL1 inhibitor, intracellular IL-1 receptor antagonist type II, intracellular interleukin-1 receptor antagonist (icIL-1ra), type II interleukin-1 receptor antagonist
- HostRabbit
- IsotypeIgG
- Protein IDP18510
- Protein NameInterleukin-1 receptor antagonist protein
- Scientific DescriptionThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hao B, Zhang Z, Lu Z, et al. Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma. Transl Oncol. 2023,27:101568. doi: 10.1016/j.tranon.2022.101568Read this paper





![Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with IL1 Receptor antagonist antibody [HL3228] (GTX640869) diluted at 1:6000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.](https://www.genetex.com/upload/website/prouct_img/normal/GTX640869/GTX640869_T-45509_20240823_WB_TPM_watermark_24082802_681.webp)
![Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with IL1 Receptor antagonist antibody [HL3366] (GTX641186) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.](https://www.genetex.com/upload/website/prouct_img/normal/GTX641186/GTX641186_T-45572_20241025_WB_TPM_watermark_24103022_910.webp)
![IL1 Receptor antagonist antibody [HL3369] detects IL1 Receptor antagonist protein by immunohistochemical analysis. Sample: Paraffin-embedded mouse tissues. IL1 Receptor antagonist stained by IL1 Receptor antagonist antibody [HL3369] (GTX641189) diluted at 1:200. Antigen Retrieval: Tris-EDTA buffer, pH 9.0, 15 min Corresponding RNA expression data for the same tissues are based on NCBI.](https://www.genetex.com/upload/website/prouct_img/normal/GTX641189/GTX641189_T-45572_20250127_IHC-P_M_Multiple_RPKM_25021923_885.webp)

