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FACS analysis of mouse macrophages (stimulated in the presence of a protein transport inhibitor) using GTX01491-07 IL23 antibody [C17.8] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.06microg (5 microl)
FACS analysis of mouse macrophages (stimulated in the presence of a protein transport inhibitor) using GTX01491-07 IL23 antibody [C17.8] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.06microg (5 microl)
FACS analysis of mouse macrophages (stimulated in the presence of a protein transport inhibitor) using GTX01491-07 IL23 antibody [C17.8] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.06microg (5 microl)

IL12B / IL12 p40 antibody [C17-8] (APC)

Research Use Only
GTX01491-07
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetIl12a
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL12B / IL12 p40 antibody [C17-8] (APC)
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    C17-8
  • Concentration
    0.2 mg/ml
  • Conjugate
    APC (Allophycocyanin)
  • Formulation
    Liquid
  • Gene ID16159
  • Target name
    Il12a
  • Target description
    interleukin 12a
  • Target synonyms
    CLMF p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12; IL-12 p35 subunit; IL-12 subunit p35; Il-12a; IL-12p35; interleukin 12a p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; p3; p35
  • Host
    Rat
  • Isotype
    IgG2a
  • Protein IDP43431
  • Protein Name
    Interleukin-12 subunit alpha
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Withasteroid B from D. metel L. regulates immune responses by modulating the JAK/STAT pathway and the IL-17+ RORgammat+ /IL-10+ FoxP3+ ratio. Su Y et al., 2017 Oct, Clin Exp Immunol
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  • CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help. Dong H et al., 2012 Apr 15, J Immunol
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  • Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus. Prabhakara R et al., 2011 Dec, Infect Immun
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  • IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. Chmielewski M et al., 2011 Sep 1, Cancer Res
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  • Antitumor and antimetastatic activity of IL-23. Lo CH et al., 2003 Jul 15, J Immunol
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  • IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. Belladonna ML et al., 2002 Jun 1, J Immunol
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  • Role of IL-12 in intrathymic negative selection. Ldviksson BR et al., 1999 Oct 15, J Immunol
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  • Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection. Kato K et al., 1996 Aug 20, Proc Natl Acad Sci U S A
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  • Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Wysocka M et al., 1995 Mar, Eur J Immunol
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