FACS analysis of mouse macrophages (stimulated in the presence of a protein transport inhibitor) using GTX01491-07 IL23 antibody [C17.8] (APC). Right panel : primary antibody Left panel : isotype control antibody amount : 0.06microg (5 microl)
IL12B / IL12 p40 antibody [C17-8] (APC)
GTX01491-07
Overview
- SupplierGeneTex
- Product NameIL12B / IL12 p40 antibody [C17-8] (APC)
- Delivery Days Customer9
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC17-8
- Concentration0.2 mg/ml
- ConjugateAPC (Allophycocyanin)
- FormulationLiquid
- Gene ID16159
- Target nameIl12a
- Target descriptioninterleukin 12a
- Target synonymsCLMF p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12; IL-12 p35 subunit; IL-12 subunit p35; Il-12a; IL-12p35; interleukin 12a p35 subunit; interleukin-12 p35 subunit; interleukin-12 subunit alpha; Ll12a; p3; p35
- HostRat
- IsotypeIgG2a
- Protein IDP43431
- Protein NameInterleukin-12 subunit alpha
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Withasteroid B from D. metel L. regulates immune responses by modulating the JAK/STAT pathway and the IL-17+ RORgammat+ /IL-10+ FoxP3+ ratio. Su Y et al., 2017 Oct, Clin Exp ImmunolRead more
- CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help. Dong H et al., 2012 Apr 15, J ImmunolRead more
- Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus. Prabhakara R et al., 2011 Dec, Infect ImmunRead more
- IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. Chmielewski M et al., 2011 Sep 1, Cancer ResRead more
- Antitumor and antimetastatic activity of IL-23. Lo CH et al., 2003 Jul 15, J ImmunolRead more
- IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. Belladonna ML et al., 2002 Jun 1, J ImmunolRead more
- Role of IL-12 in intrathymic negative selection. Ldviksson BR et al., 1999 Oct 15, J ImmunolRead more
- Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection. Kato K et al., 1996 Aug 20, Proc Natl Acad Sci U S ARead more
- Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Wysocka M et al., 1995 Mar, Eur J ImmunolRead more