IL12B / IL12 p40 antibody [C17-8] (PE)

Su Y, Wang Q, Yang B, et al. Withasteroid B from D. metel L. regulates immune responses by modulating the JAK/STAT pathway and the IL-17(+) RORγt(+) /IL-10(+) FoxP3(+) ratio. Clin Exp Immunol. 2017,190(1):40-53. doi: 10.1111/cei.12998

Dong H, Franklin NA, Roberts DJ, et al. CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help. J Immunol. 2012,188(8):3829-38. doi: 10.4049/jimmunol.1103329

Prabhakara R, Harro JM, Leid JG, et al. Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus. Infect Immun. 2011,79(12):5010-8. doi: 10.1128/IAI.05571-11

Chmielewski M, Kopecky C, Hombach AA, et al. IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. Cancer Res. 2011,71(17):5697-706. doi: 10.1158/0008-5472.CAN-11-0103

Lo CH, Lee SC, Wu PY, et al. Antitumor and antimetastatic activity of IL-23. J Immunol. 2003,171(2):600-7.

Belladonna ML, Renauld JC, Bianchi R, et al. IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. J Immunol. 2002,168(11):5448-54.

Lúdvíksson BR, Ehrhardt RO, Strober W. Role of IL-12 in intrathymic negative selection. J Immunol. 1999,163(8):4349-59.

Kato K, Shimozato O, Hoshi K, et al. Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection. Proc Natl Acad Sci U S A. 1996,93(17):9085-9.

Wysocka M, Kubin M, Vieira LQ, et al. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur J Immunol. 1995,25(3):672-6.