IL17 antibody [4H48]
GTX53353
ApplicationsWestern Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
TargetIl17a
Overview
- SupplierGeneTex
- Product NameIL17 antibody [4H48]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4H48
- Concentration500 ug/ml
- ConjugateUnconjugated
- Gene ID16171
- Target nameIl17a
- Target descriptioninterleukin 17A
- Target synonymsCtl; Ctla; Ctla8; Ctla-8; cytotoxic T-lymphocyte-associated antigen 8; Il; IL-; Il17; IL-17; IL-17A; interleukin-17A
- HostRat
- IsotypeIgG2
- Protein IDQ62386
- Protein NameInterleukin-17A
- Scientific DescriptionThis gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Sep 2015]
- ReactivityMouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Interleukin (IL)-17A Promotes Angiogenesis in an Experimental Corneal Neovascularization Model. Liu G et al., 2017 Mar, Curr Eye ResRead more