IL23A / IL-23 p19 Antibody (clone mh066, Preservative Free)

LifeSpan BioSciences

IL23A / IL-23 p19 Antibody (clone mh066, Preservative Free)

14

Human IL-23. Has cross-reactivity with with Cynomolgus IL-23 & IL12B Heterodimer Protein in ELISA assay. No cross-reactivity with Mouse IL-23 & IL12B Heterodimer or Rat IL-23 & IL12B Heterodimer Protein in ELISA assay

Block: In a functional ELISA which immobilized recombinant Human IL23R/Fc Chimera at 8 ug/ml (100 microL/well) in the plate, the Rabbit anti-Human IL23a Monoclonal Antibody can block the binding of 0.5 ug/ml of biotinylated recombinant Human IL23A & Human IL12B Heterodimer Protein to human IL23R, the EC50 is 0.59 ug/ml. Neutralization: The neutralization activity of antibody is Measured by its ability to neutralize IL23-induced IL17A secretion in mouse splenocytes. The Neutralization titer (IC50) is typically 10.0-15.0 ng/mL in the presence of 10 ng/mL Recombinant Human IL-23 and ConA (1 microg/mL ). Please Note: Optimal concentrations/dilutions should be determined by the end user.. ELISA (8 µg/ml), Neut (10 ng/ml) Block: In a functional ELISA which immobilized recombinant Human IL23R/Fc Chimera at 8 ug/ml (100 µL/well) in the plate, the Rabbit anti-Human IL23a Monoclonal Antibody can block the binding of 0.5 ug/ml of biotinylated recombinant Human IL23A & Human IL12B Heterodimer Protein to human IL23R, the EC50 is 0.59 ug/ml. Neutralization: The neutralization activity of antibody is Measured by its ability to neutralize IL23­induced IL17A secretion in mouse splenocytes. The Neutralization titer (IC50) is typically 10.0­15.0 ng/mL in the presence of 10 ng/mL Recombinant Human IL-23 and ConA (1 µg/mL ). Please Note: Optimal concentrations/dilutions should be determined by the end user.

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

mh066

Unconjugated

...

IL23A

interleukin 23 subunit alpha

IL-23; IL-23 subunit alpha; IL-23A; IL-23-A; IL23P19; IL-23p19; interleukin 23 p19 subunit; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; P19; SGRF

Mouse

IgG1

Human

-20°C or -80°C,2°C to 8°C

12352203