IL6 antibody

Name: IL6 antibody
SKU: GTX17623_G10
Availability: BackOrder

GTX17623

ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetIl6

Overview

Supplier
GeneTex
Product Name
IL6 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:300-1000. IHC-P: 1:50-400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID16193
Target name
Il6
Target description
interleukin 6
Target synonyms
Il-6, interleukin-6, B-cell hybridoma growth factor, interleukin HP-1
Host
Rabbit
Isotype
IgG
Protein IDP08505
Protein Name
Interleukin-6
Scientific Description
This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Chu W, Li YL, Li JJ, et al. Guiqi Baizhu prescription ameliorates cytarabine-induced intestinal mucositis by targeting JAK2 to inhibit M1 macrophage polarization. Biomed Pharmacother. 2023,164:114902. doi: 10.1016/j.biopha.2023.114902
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Setyo Nugroho GM, Marhana IA, Kusumastuti EH, et al. Interleukin-6 (IL-6) expression of lung tissue in COVID-19 patient severity through core biopsy post mortem. Ann Med Surg (Lond). 2022,82:104648. doi: 10.1016/j.amsu.2022.104648
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Al-Roub A, Al Madhoun A, Akhter N, et al. IL-1β and TNFα Cooperativity in Regulating IL-6 Expression in Adipocytes Depends on CREB Binding and H3K14 Acetylation. Cells. 2021,10(11). doi: 10.3390/cells10113228
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Lu HY, Hsu HL, Li CH, et al. Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway. Antioxidants (Basel). 2021,10(5). doi: 10.3390/antiox10050682
Read this paper