
WB analysis of mouse brain tissue lysate using GTX37399 IL6 Receptor antibody.
IL6 Receptor antibody
GTX37399
Overview
- SupplierGeneTex
- Product NameIL6 Receptor antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID3570
- Target nameIL6R
- Target descriptioninterleukin 6 receptor
- Target synonymsCD126; CD126 antigen; gp80; HIES5; IL-1Ra; IL-6 receptor subunit alpha; IL6Q; IL6QTL; IL-6R; IL-6R-1; IL6RA; IL-6RA; IL6RQ; interleukin-6 receptor subunit alpha; membrane glycoprotein 80
- HostRabbit
- IsotypeIgG
- Protein IDP08887
- Protein NameInterleukin-6 receptor subunit alpha
- Scientific DescriptionThis gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Experimental venous thrombus resolution is driven by IL-6 mediated monocyte actions.Read more