ILK antibody [N1C1]
GTX101691
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetILK
Overview
- SupplierGeneTex
- Product NameILK antibody [N1C1]
- Delivery Days Customer9
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.8 mg/ml
- ConjugateUnconjugated
- Gene ID3611
- Target nameILK
- Target descriptionintegrin linked kinase
- Target synonyms59 kDa serine/threonine-protein kinase; beta-integrin-linked kinase; epididymis secretory protein Li 28; HEL-S-28; ILK-1; ILK-2; integrin-linked kinase-2; integrin-linked protein kinase; P59; p59ILK
- HostRabbit
- IsotypeIgG
- Scientific DescriptionTransduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat, Zebra Fish
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. Chen YL et al., 2021 Jan 12, Sci RepRead more
- The Impact of Integrin-Mediated Matrix Adhesion on Cisplatin Resistance of W1 Ovarian Cancer Cells. Wantoch von Rekowski K et al., 2019 Nov 26, BiomoleculesRead more
- Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin beta1. Yen YC et al., 2015 Dec 8, OncotargetRead more
- Novel link of anti-apoptotic ATF3 with pro-apoptotic CTMP in the ischemic brain. Huang CY et al., 2015 Apr, Mol NeurobiolRead more