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ProductsBack/ILK antibody [N1C1]

ILK antibody [N1C1]

GTX101691
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetILK
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Overview

  • Supplier
    GeneTex
  • Product Name
    ILK antibody [N1C1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.8 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3611
  • Target name
    ILK
  • Target description
    integrin linked kinase
  • Target synonyms
    59 kDa serine/threonine-protein kinase; beta-integrin-linked kinase; epididymis secretory protein Li 28; HEL-S-28; ILK-1; ILK-2; integrin-linked kinase-2; integrin-linked protein kinase; P59; p59ILK
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13418
  • Protein Name
    Integrin-linked protein kinase
  • Scientific Description
    Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Upregulation of integrin-linked kinase enhances tumor progression in gemcitabine-resistant pancreatic cancer.
    Read more
  • Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. Chen YL et al., 2021 Jan 12, Sci Rep
    Read more
  • The Impact of Integrin-Mediated Matrix Adhesion on Cisplatin Resistance of W1 Ovarian Cancer Cells. Wantoch von Rekowski K et al., 2019 Nov 26, Biomolecules
    Read more
  • Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin beta1. Yen YC et al., 2015 Dec 8, Oncotarget
    Read more
  • Novel link of anti-apoptotic ATF3 with pro-apoptotic CTMP in the ischemic brain. Huang CY et al., 2015 Apr, Mol Neurobiol
    Read more

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