ILK antibody [N1C1]
GTX101691
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetILK
Overview
- SupplierGeneTex
- Product NameILK antibody [N1C1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.8 mg/ml
- ConjugateUnconjugated
- Gene ID3611
- Target nameILK
- Target descriptionintegrin linked kinase
- Target synonymsHEL-S-28, ILK-1, ILK-2, P59, p59ILK, scaffold protein ILK, 59 kDa serine/threonine-protein kinase, beta-integrin-linked kinase, epididymis secretory protein Li 28, inactive integrin-linked kinase, integrin-linked kinase-2, integrin-linked protein kinase
- HostRabbit
- IsotypeIgG
- Protein IDQ13418
- Protein NameScaffold protein ILK
- Scientific DescriptionTransduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Murase H, Matsuo Y, Denda Y, et al. Upregulation of integrin‑linked kinase enhances tumor progression in gemcitabine‑resistant pancreatic cancer. Oncol Rep. 2023,50(3):pii: 164. doi: 10.3892/or.2023.8601.Read this paper
- Chen YL, Yen YC, Jang CW, et al. Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. Sci Rep. 2021,11(1):644. doi: 10.1038/s41598-020-80060-3Read this paper
- Wantoch von Rekowski K, König P, Henze S, et al. The Impact of Integrin-Mediated Matrix Adhesion on Cisplatin Resistance of W1 Ovarian Cancer Cells. Biomolecules. 2019,9(12). doi: 10.3390/biom9120788Read this paper
- Yen YC, Hsiao JR, Jiang SS, et al. Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1. Oncotarget. 2015,6(39):41837-55. doi: 10.18632/oncotarget.5995Read this paper
- Huang CY, Chen JJ, Wu JS, et al. Novel link of anti-apoptotic ATF3 with pro-apoptotic CTMP in the ischemic brain. Mol Neurobiol. 2015,51(2):543-57. doi: 10.1007/s12035-014-8710-0Read this paper





![FACS analysis of Jurkat cells using GTX01046 ILK antibody [SC68-04]. Red : primary antibody Black : unlabelled control Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX01046/GTX01046_20200303_FACS_302_w_23053121_875.webp)
![ELISA analysis of antigen using GTX60645 ILK antibody [3A9]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60645/GTX60645_20170912_ELISA_w_23061123_737.webp)