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IMP3 antibody [EP286]

Research Use Only
GTX01720
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetIGF2BP3
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Overview

  • Supplier
    GeneTex
  • Product Name
    IMP3 antibody [EP286]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    EP286
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID10643
  • Target name
    IGF2BP3
  • Target description
    insulin like growth factor 2 mRNA binding protein 3
  • Target synonyms
    cancer/testis antigen 98; CT98; IGF2 mRNA-binding protein 3; IGF-II mRNA-binding protein 3; IMP3; IMP-3; insulin-like growth factor 2 mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KOC; KOC1; VICKZ family member 3; VICKZ3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00425
  • Protein Name
    Insulin-like growth factor 2 mRNA-binding protein 3
  • Scientific Description
    The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5 UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Well-differentiated papillary mesothelioma: A 17-year single institution experience with a series of 75 cases. Sun M et al., 2019 Feb, Ann Diagn Pathol
    Read more
  • IMP3 as a prognostic biomarker in patients with malignant peritoneal mesothelioma. Hui S et al., 2018 Nov, Hum Pathol
    Read more