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INCB18424

M1787
AbMole BioScience
CAS Number941678-49-5
DownloadDatasheet
Product group Chemicals
Estimated Purity0.9935
Molecular Weight306.37
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    INCB18424
  • Delivery Days Customer
    9
  • CAS Number
    941678-49-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9935
  • Molecular Formula
    C17H18N6
  • Molecular Weight
    306.37
  • Scientific Description
    Ruxolitinib (INCB018424) is a first-in-class, potent, selective JAK1/2 inhibitor with an IC50 of 3.3 nM/2.8 nM. It is more than 130-fold more selective for JAK1, JAK2, and JAK3 than JAK3. It can be used in studies related to pemphigus, myelofibrosis and vitiligo.
  • SMILES
    N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4
  • UNSPSC
    12352200