INPP5F Antibody, Biotin conjugated

Cusabio

INPP5F Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

INPP5F

inositol polyphosphate-5-phosphatase F

MSTP007, MSTPO47, SAC2, hSAC2, phosphatidylinositide phosphatase SAC2, Sac domain-containing inositol phosphatase 2, sac domain-containing phosphoinositide 4-phosphatase 2, sac domain-containing phosphoinositide 5-phosphatase 2

Rabbit

IgG

Phosphatidylinositide phosphatase SAC2

Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (By similarity). May play a role as negative regulator of axon regeneration after central nervous system injuries (By similarity).

Human

-20°C or -80°C

41116161