InVivoMAb anti-human CD4

Moolla N, Killick M, Papathanasopoulos M, et al. Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry. Biochim Biophys Acta. 2016,1860(9):1854-63. doi: 10.1016/j.bbagen.2016.05.030

Mayer CT, Huntenburg J, Nandan A, et al. CD4 blockade directly inhibits mouse and human CD4(+) T cell functions independent of Foxp3(+) Tregs. J Autoimmun. 2013,47:73-82. doi: 10.1016/j.jaut.2013.08.008

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Mack CL, Tucker RM, Sokol RJ, et al. Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. Pediatr Res. 2004,56(1):79-87.

Geijtenbeek TB, Kwon DS, Torensma R, et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell. 2000,100(5):587-97.

Moir S, Lapointe R, Malaspina A, et al. CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral reservoir. J Virol. 1999,73(10):7972-80.