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InVivoMAb anti-rat CD4
BE0308
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-rat CD4
- Delivery Days Customer7
- ApplicationsFlow Cytometry, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOX-38
- Concentration4-11 mg/ml
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThe OX-38 monoclonal antibody reacts with the rat CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The OX-38 antibody has been reported to deplete CD4+ T cells in vivo.
- ReactivityRat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Vaccination to prevent T cell subversion can protect against persistent hepacivirus infection. Hartlage AS et al., 2019 Mar 7, Nat CommunRead more
- Distribution of bone-marrow-derived endothelial and immune cells in a murine colitis-associated colorectal cancer model. Xiao CX et al., 2013, PLoS OneRead more
- Permanent CNI treatment for prevention of renal allograft rejection in sensitized hosts can be replaced by regulatory T cells. Siepert A et al., 2012 Sep, Am J TransplantRead more
- Antibodies contribute to effective vaccination against respiratory infection by type A Francisella tularensis strains. Mara-Koosham G et al., 2011 Apr, Infect ImmunRead more
- alpha1,2Fucosyltransferase increases resistance to apoptosis of rat colon carcinoma cells. Goupille C et al., 2000 Apr, GlycobiologyRead more
- Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the rat. Westermann W et al., 1999 May, Int J Radiat BiolRead more
- Single dose anti-CD4 monoclonal antibody for induction of tolerance to cardiac allograft in high- and low-responder rat strain combinations. Qi Z et al., 1997 Sep, Transpl ImmunolRead more
Related products
Product group Antibodies
References
InVivoPlus anti-rat CD4BP0308
ApplicationsFlow Cytometry, Other Application
ReactivityRat
- SizePrice
