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InVivoMAb anti-human LFA-1alpha (CD11a)

Research Use Only
BE0005
Bio X Cell
ApplicationsNeutralisation/Blocking
Product group Antibodies
ReactivityHuman
Price on request
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Packing Size
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-human LFA-1alpha (CD11a)
  • Delivery Days Customer
    7
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    TS-1/22.1.1.13
  • Concentration
    4-11 mg/ml
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The TS-1/22.1.1.13 monoclonal antibody reacts with human LFA-1α(lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. LFA-1αand CD18 combine to form LFA-1 a 180 kDa glycoprotein and a member of the integrin family. LFA-1 is expressed on the surface of all leukocytes including lymphocytes monocytes macrophages and granulocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands ICAM-1 (CD54) ICAM-2 (CD102) and ICAM-3 (CD50) and also functions in lymphocyte costimulatory signaling.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses. Kitchens WH et al., 2012 May 27, Transplantation
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