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InVivoMAb anti-human LFA-1alpha (CD11a)
BE0005
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-human LFA-1alpha (CD11a)
- Delivery Days Customer7
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDTS-1/22.1.1.13
- Concentration4-11 mg/ml
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe TS-1/22.1.1.13 monoclonal antibody reacts with human LFA-1α(lymphocyte function-associated antigen 1 alpha) also known as integrin alpha L chain and CD11a. LFA-1αand CD18 combine to form LFA-1 a 180 kDa glycoprotein and a member of the integrin family. LFA-1 is expressed on the surface of all leukocytes including lymphocytes monocytes macrophages and granulocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands ICAM-1 (CD54) ICAM-2 (CD102) and ICAM-3 (CD50) and also functions in lymphocyte costimulatory signaling.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses. Kitchens WH et al., 2012 May 27, TransplantationRead more
