InVivoMAb anti-human MHC Class I (HLA-A, HLA-B, HLA-C)

HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging FcgammaRs. Valenzuela NM et al., 2013 Jun 15, J Immunol

Blockade of p-selectin is sufficient to reduce MHC I antibody-elicited monocyte recruitment in vitro and in vivo. Valenzuela NM et al., 2013 Feb, Am J Transplant