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InVivoMAb anti-mouse Nonclassical MHC Class I molecule Qa-1b
BE0165
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityMouse
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-mouse Nonclassical MHC Class I molecule Qa-1b
- Delivery Days Customer7
- ApplicationsImmunoFluorescence, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4C2.4A7.5H11
- Concentration4-11 mg/ml
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe 4C2.4A7.5H11 monoclonal antibody reacts with the mouse non-classical MHC class I molecule Qa-1b. Qa-1b is the functional homolog of HLA-E in humans and is characterized by its limited polymorphisms and small peptide repertoire. Qa-1b interacts with NK cells through the CD94/NKG2 family of receptors. Upon binding, Qa-1b signals NK cells not to engage in cell lysis.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Infection-induced expansion of a MHC Class Ib-dependent intestinal intraepithelial gammadelta T cell subset. Davies A et al., 2004 Jun 1, J ImmunolRead more
- Functional analysis of the molecular factors controlling Qa1-mediated protection of target cells from NK lysis. Gays F et al., 2001 Feb 1, J ImmunolRead more
