Bio-Connect
Product image
Product image
Product image

InVivoMAb anti-mouse Nonclassical MHC Class I molecule Qa-1b

Research Use Only
BE0165
Bio X Cell
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityMouse
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse Nonclassical MHC Class I molecule Qa-1b
  • Delivery Days Customer
    7
  • Applications
    ImmunoFluorescence, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4C2.4A7.5H11
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The 4C2.4A7.5H11 monoclonal antibody reacts with the mouse non-classical MHC class I molecule Qa-1b. Qa-1b is the functional homolog of HLA-E in humans and is characterized by its limited polymorphisms and small peptide repertoire. Qa-1b interacts with NK cells through the CD94/NKG2 family of receptors. Upon binding, Qa-1b signals NK cells not to engage in cell lysis.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Infection-induced expansion of a MHC Class Ib-dependent intestinal intraepithelial gammadelta T cell subset. Davies A et al., 2004 Jun 1, J Immunol
    Read more
  • Functional analysis of the molecular factors controlling Qa1-mediated protection of target cells from NK lysis. Gays F et al., 2001 Feb 1, J Immunol
    Read more

Related products

Product image
Product group Antibodies
References
Bio X Cell
  • SizePrice
Product image
Product group Chemicals
Bio X Cell
  • SizePrice