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WB analysis of A20 cell lysate using GTX30005 IRE1 alpha antibody. Lane A : 0.5 microg/ml Lane B : 1microg/ml Lane C : 2microg/ml
WB analysis of A20 cell lysate using GTX30005 IRE1 alpha antibody. Lane A : 0.5 microg/ml Lane B : 1microg/ml Lane C : 2microg/ml
WB analysis of A20 cell lysate using GTX30005 IRE1 alpha antibody. Lane A : 0.5 microg/ml Lane B : 1microg/ml Lane C : 2microg/ml

IRE1 alpha antibody

GTX30005
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetERN1
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Overview

  • Supplier
    GeneTex
  • Product Name
    IRE1 alpha antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.5-2 microg/ml. ICC/IF: 1-2 microg/ml. IHC-P: 5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2081
  • Target name
    ERN1
  • Target description
    endoplasmic reticulum to nucleus signaling 1
  • Target synonyms
    IRE1, IRE1P, IRE1a, hIRE1p, serine/threonine-protein kinase/endoribonuclease IRE1, ER to nucleus signalling 1, inositol-requiring 1, inositol-requiring enzyme 1, inositol-requiring protein 1, ire1-alpha, protein kinase/endoribonuclease
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75460
  • Protein Name
    Serine/threonine-protein kinase/endoribonuclease IRE1
  • Scientific Description
    The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lee EJ, Chan P, Chea L, et al. ATF6 is required for efficient rhodopsin clearance and retinal homeostasis in the P23H rho retinitis pigmentosa mouse model. Sci Rep. 2021,11(1):16356. doi: 10.1038/s41598-021-95895-7
    Read this paper
  • Huang CY, Deng JS, Huang WC, et al. Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Nutrients. 2020,12(6). doi: 10.3390/nu12061742
    Read this paper
  • Chen JF, Tsai YT, Lai YH, et al. Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. J Pharm Biomed Anal. 2020,187:113142. doi: 10.1016/j.jpba.2020.113142
    Read this paper

Datasheet

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