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WB analysis of A20 cell lysate using GTX30005 IRE1 alpha antibody. Lane A : 0.5 microg/ml Lane B : 1microg/ml Lane C : 2microg/ml
WB analysis of A20 cell lysate using GTX30005 IRE1 alpha antibody. Lane A : 0.5 microg/ml Lane B : 1microg/ml Lane C : 2microg/ml
WB analysis of A20 cell lysate using GTX30005 IRE1 alpha antibody. Lane A : 0.5 microg/ml Lane B : 1microg/ml Lane C : 2microg/ml

IRE1 alpha antibody

Research Use Only
GTX30005
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetERN1
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Overview

  • Supplier
    GeneTex
  • Product Name
    IRE1 alpha antibody - KO/KD Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.5-2 microg/ml. ICC/IF: 1-2 microg/ml. IHC-P: 5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2081
  • Target name
    ERN1
  • Target description
    endoplasmic reticulum to nucleus signaling 1
  • Target synonyms
    ER to nucleus signalling 1; hIRE1p; inositol-requiring 1; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; ire1-alpha; IRE1P; protein kinase/endoribonuclease; serine/threonine-protein kinase/endoribonuclease IRE1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75460
  • Protein Name
    Serine/threonine-protein kinase/endoribonuclease IRE1
  • Scientific Description
    The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • ATF6 is required for efficient rhodopsin clearance and retinal homeostasis in the P23H rho retinitis pigmentosa mouse model. Lee EJ et al., 2021 Aug 11, Sci Rep
    Read more
  • Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Huang CY et al., 2020 Jun 10, Nutrients
    Read more
  • Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. Chen JF et al., 2020 Aug 5, J Pharm Biomed Anal
    Read more