Ixazomib (MLN2238)

Selleck Chemicals

Ixazomib (MLN2238) [1072833-77-2]

9

1072833-77-2

Research Use Only

...

Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (beta5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (beta1) and trypsin-like (beta2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3.

-80°C

51202000