Ixazomib (MLN2238) [1072833-77-2]
S2180
CAS Number1072833-77-2
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameIxazomib (MLN2238) [1072833-77-2]
- Delivery Days Customer9
- CAS Number1072833-77-2
- CertificationResearch Use Only
- Scientific DescriptionIxazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (bèta5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (bèta1) and trypsin-like (bèta2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3.
- UNSPSC12352200