JNJ-28583113 [2765255-93-2]

TargetMol Chemicals

JNJ-28583113 [2765255-93-2]

16

Research Use Only

JNJ-28583113

C19H21F3N2O2

366.38

JNJ-28583113, a TRPM2 antagonist with brain permeability, inhibits the phosphorylation of GSK3alpha and beta subunits, thereby protecting cells from oxidative stress-induced cell death. Additionally, it suppresses cytokine release in response to pro-inflammatory stimuli in microglia [1].

3 years

O=C(OCC)CN1N=C(C=2C=CC(=CC2)C(F)(F)F)C3=C1CCCCC3

-20°C

12352200