JNJ-63576253 (TRC-253)

Biorbyt

JNJ-63576253 (TRC-253) [2110426-27-0]

10

2110426-27-0

Research Use Only

C23H21F3N6O2S

502.51

JNJ-63576253 (TRC-253) is a potent and selective androgen receptor (AR) Antagonist with IC50 of 6.9 nM. JNJ-63576253 displays robust inhibition in WT and LBD-mutated, enzalutamide-resistant models of prostate cancer.

C(F)(F)(C1=CC(N2C(N(C3C=CC(=NC=3)OC3CCNCC3)C3(CCC3)C2=O)=S)=CN=C1C#N)F

12352200