(+)-JQ-1

MedChem Express

(+)-JQ-1 [1268524-70-4]

10

1268524-70-4

Research Use Only

99.90

C23H25ClN4O2S

456.99

(+)-JQ-1 (JQ1) is a potent, specific, and reversible BET bromodomain inhibitor, with IC 50 s of 77 and 33 nM for the first and second bromodomain ( BRD4(1/2) ) [1] . (+)-JQ-1 also activates autophagy [2] .

O=C(C[C@H]1C2=NN=C(N2C3=C(C(C4=CC=C(C=C4)Cl)=N1)C(C)=C(S3)C)C)OC(C)(C)C

-20°C,2°C to 8°C

12352200