(+)-JQ1
M2167
CAS Number1268524-70-4
Product group Chemicals
Estimated Purity0.988
Molecular Weight456.99
Overview
- SupplierAbMole BioScience
- Product Name(+)-JQ1
- Delivery Days Customer9
- CAS Number1268524-70-4
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity0.988
- Molecular FormulaC23H25ClN4O2S
- Molecular Weight456.99
- Scientific Description(+)-JQ1 is a BET bromodomain inhibitor that acts on BRD4(2) with an IC50 of 33 nM and binds to all bromodomain domains in the BET family, but not to bromodomain domains outside the BET family. JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway, and JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway.
- SMILESCC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(=O)OC(C)(C)C)N=C2C4=CC=C(Cl)C=C4)C
- UNSPSC12352200
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