More than 130 suppliers

In-house tech support

Call +31 (0)26 326 44 50

Bio-Connect

Products
Products
Antibodies
Chemicals
Proteins / Signaling Molecules
Assays
DNA / RNA / Vectors
Cell Culture
Genome Editing and Engineering
Molecular Biology
Lysates / Extracts
Expression
Labware / Accesories
Body Products
Technique Specific Products
Arrays / Slides
Diagnostic
Biologicals
Microbiology
Promotions
All product groups
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Suppliers
Suppliers
Life Sciences
Diagnostics
Services
Become a partner
All Suppliers
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Industries
Industries
Biotech, Pharma & CRO
Academia
Diagnostics
Environment
Food
Veterinary
All industries
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
News

Website
Events
Promotions
About us
About us
Our company
Our team
For suppliers
Vacatures
Events
Promotions
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Contact
Contact
Headquarters
Customer Service
Technical support
Accountmanagers
FAQ
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?

ProductsBack/(-)-JQ1 [1268524-71-5]

(-)-JQ1 [1268524-71-5]

(-)-JQ1 [1268524-71-5]

27335

CAS Number1268524-71-5

Product group Chemicals

Molecular Weight457.0 kDa

Overview

Supplier
BPS Bioscience
Product Name
(-)-JQ1 [1268524-71-5]
Delivery Days Customer
7
CAS Number
1268524-71-5
Certification
Research Use Only
Molecular Formula
C23H25ClN4O2S
Molecular Weight
457.0 kDa
Scientific Description
(-)-JQ1 is the inactive stereoisomer of the potent, cell-permeable, small molecule bromodomain inhibitor (+)-JQ1 that competitively binds to acetyl-lysine recognition motifs. (+)-JQ1 competitively binds to the bromodomain displacing the BRD4 fusion oncoprotein from chromatin, which induces squamous differentiation and specific anti-proliferative effect in BRD4-dependent cell lines and patient-derived xenograft models. However, study results have shown that (-)-JQ1 fails to significantly interact with any bromodomain tested and exhibits inhibition against BRD4(1) with and IC50 of 10,000 nM.
UNSPSC
12161509

FAQ

Go to our frequently asked questions