Western Blot analysis of Mouse brain and Human fetal brain tissue, Human brain malignant glioma tissue using KIF3A Polyclonal Antibody at dilution of 1:500
Western Blot analysis of Mouse brain and Human fetal brain tissue, Human brain malignant glioma tissue using KIF3A Polyclonal Antibody at dilution of 1:500
KIF3A Polyclonal Antibody
E-AB-10420
Product group Antibodies
Overview
- SupplierElabscience
- Product NameKIF3A Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.2mg/ml
- Scientific DescriptionKinesin-like protein KIF3Ais aproteinthat in humans is encoded by theKIF3Agene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.
- UNSPSC12352203