KIF3A Polyclonal Antibody

Elabscience

KIF3A Polyclonal Antibody

12

Western Blot

ELISA WB IHC

Research Use Only

Polyclonal

0.2 mg/ml

Unconjugated

KIF3A

kinesin family member 3A

FLA10, KLP-20, kinesin-like protein KIF3A, kinesin family protein 3A, microtubule plus end-directed kinesin motor 3A

Rabbit

IgG

Kinesin-like protein KIF3A

Kinesin-like protein KIF3Ais aproteinthat in humans is encoded by theKIF3Agene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.

-20°C

41116161