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Detection of human Ku70 protein in HeLa whole cell lysate using GeneTex Ku70 1.5 monoclonal antibody GTX70271.
Detection of human Ku70 protein in HeLa whole cell lysate using GeneTex Ku70 1.5 monoclonal antibody GTX70271.
Detection of human Ku70 protein in HeLa whole cell lysate using GeneTex Ku70 1.5 monoclonal antibody GTX70271.

Ku70 antibody [1.5]

GTX70271
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetXRCC6
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Overview

  • Supplier
    GeneTex
  • Product Name
    Ku70 antibody [1.5]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1.5
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2547
  • Target name
    XRCC6
  • Target description
    X-ray repair cross complementing 6
  • Target synonyms
    CTC75, CTCBF, G22P1, KU70, ML8, TLAA, X-ray repair cross-complementing protein 6, 5'-dRP lyase Ku70, 5'-deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II, 70 kDa subunit, CTC box binding factor 75 kDa subunit, DNA repair protein XRCC6, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, X-ray repair complementing defective repair in Chinese hamster cells 6, lupus Ku autoantigen protein p70, thyroid autoantigen 70kD (Ku antigen), thyroid autoantigen 70kDa (Ku antigen), thyroid-lupus autoantigen p70
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP12956
  • Protein Name
    X-ray repair cross-complementing protein 6
  • Scientific Description
    The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Jalili P, Bowen D, Langenbucher A, et al. Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots. Nat Commun. 2020,11(1):2971. doi: 10.1038/s41467-020-16802-8
    Read this paper
  • Nguyen HD, Leong WY, Li W, et al. Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes. Cancer Res. 2018,78(18):5363-5374. doi: 10.1158/0008-5472.CAN-17-3970
    Read this paper