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L-2-Hydroxyglutaric acid [13095-48-2]

HY-113039
MedChem Express
CAS Number13095-48-2
Product group Chemicals
Estimated Purity95.0
Molecular Weight148.11
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Overview

  • Supplier
    MedChem Express
  • Product Name
    L-2-Hydroxyglutaric acid [13095-48-2]
  • Delivery Days Customer
    9
  • CAS Number
    13095-48-2
  • Certification
    Research Use Only
  • Concentration
    67.52 mM
  • Estimated Purity
    95.0
  • Molecular Formula
    C5H8O5
  • Molecular Weight
    148.11
  • Scientific Description
    L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].
  • SMILES
    O=C(O)[C@@H](O)CCC(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200