L1CAM antibody

GeneTex

L1CAM antibody [UJ181.4]

9

Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain.

IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 136 kDa. Optimal dilutions/concentrations should be determined by the end user.

ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

0.6 mg/ml

Unconjugated

Liquid

L1CAM

L1 cell adhesion molecule

antigen identified by monoclonal antibody R1; CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAML1; N-CAM-L1; NCAM-L1; neural cell adhesion molecule L1; S10; SPG1

Mouse

IgG1

Neural cell adhesion molecule L1

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203