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Lamin B1 antibody

GTX103292
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetLMNB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Lamin B1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.64 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4001
  • Target name
    LMNB1
  • Target description
    lamin B1
  • Target synonyms
    ADLD, ADLDAT, LMN, LMN2, LMNB, MCPH26, lamin-B1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP20700
  • Protein Name
    Lamin-B1
  • Scientific Description
    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Wang BY, Shen HT, Lee YL, et al. Inhibition of Na+/H+ exchanger (NHE) 7 by 5-(N-ethyl-N-isopropyl)-Amiloride displays anti-cancer activity in non-small cell lung cancer by disrupting cancer stem cell activity and downregulating PD-L1 expression. Am J Cancer Res. 2023,13(10):4721-4733.
    Read this paper
  • An M, Lim YH. Surface-exposed chaperonin 60 derived from Propionibacterium freudenreichii MJ2 inhibits adipogenesis by decreasing the expression of C/EBPα/PPARγ. Sci Rep. 2023,13(1):19251. doi: 10.1038/s41598-023-46436-x
    Read this paper
  • Ceraolo MG, Romero-Medina MC, Gobbato S, et al. HPV38 impairs UV-induced transcriptional activation of the IL-18 pro-inflammatory cytokine. mSphere. 2023,8(6):e0045023. doi: 10.1128/msphere.00450-23
    Read this paper
  • Hirasawa I, Odagiri H, Park G, et al. Anti-inflammatory effects of cold atmospheric plasma irradiation on the THP-1 human acute monocytic leukemia cell line. PLoS One. 2023,18(10):e0292267. doi: 10.1371/journal.pone.0292267
    Read this paper
  • Venuti A, Romero-Medina MC, Melita G, et al. Lyon IARC Polyomavirus Displays Transforming Activities in Primary Human Cells. J Virol. 2022,96(14):e0206121. doi: 10.1128/jvi.02061-21
    Read this paper
  • Yang CC, Chang CH, Chen HL, et al. CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA. Cell Rep. 2022,38(10):110472. doi: 10.1016/j.celrep.2022.110472
    Read this paper
  • Gillotin S. Isolation of Chromatin-bound Proteins from Subcellular Fractions for Biochemical Analysis. Bio Protoc. 2018,8(19):e3035. doi: 10.21769/BioProtoc.3035
    Read this paper
  • Guo SP, Chang HC, Lu LS, et al. Activation of kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2/antioxidant response element pathway by curcumin enhances the anti-oxidative capacity of corneal endothelial cells. Biomed Pharmacother. 2021,141:111834. doi: 10.1016/j.biopha.2021.111834
    Read this paper
  • Silva B, Arora R, Bione S, et al. TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells. Nat Commun. 2021,12(1):3760. doi: 10.1038/s41467-021-24097-6
    Read this paper
  • Cao S, Meng X, Li Y, et al. Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages. Front Immunol. 2021,12:632864. doi: 10.3389/fimmu.2021.632864
    Read this paper

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