LBP antibody [6G3]

GeneTex

LBP antibody [6G3]

9

Functional Assay, ImmunoPrecipitation, ELISA

Research Use Only

Monoclonal

6G3

100 ug/ml

Unconjugated

LBP

lipopolysaccharide binding protein

BPI fold containing family D, member 2; BPIFD2; lipopolysaccharide-binding protein; LPS-binding protein

Mouse

IgG1

Lipopolysaccharide-binding protein

The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]

2°C to 8°C

12352203