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Chemical Structure
Chemical Structure
Chemical Structure

LC-2

Research Use Only
82058
BPS Bioscience
CAS Number2502156-03-6
Product group Chemicals
Molecular Weight1132.8 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    LC-2
  • Delivery Days Customer
    7
  • CAS Number
    2502156-03-6
  • Certification
    Research Use Only
  • Molecular Formula
    C59H71ClFN11O7S
  • Molecular Weight
    1132.8 Da
  • Scientific Description
    LC-2 is a von Hippel-Lindau-based PROTAC which can degrade endogenous KRAS G12C. It covalently binds KRAS G12C with a MARTX849 warhead and recruits the E3 ligase VHL which degrades the KRAS G12C and suppresses MAPK signaling in homozygous and heterozygous KRAS G12C cell lines.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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