WB analysis of arsenic trioxide treated U87-MG cell lysate using GTX82986 LC3B antibody.
WB analysis of arsenic trioxide treated U87-MG cell lysate using GTX82986 LC3B antibody.
LC3B antibody
GTX82986
ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMAP1LC3B
Overview
- SupplierGeneTex
- Product NameLC3B antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. ICC/IF: 0.1 - 2 microg/ml. IHC-P: 1:200 - 1:400. IHC-Fr: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID81631
- Target nameMAP1LC3B
- Target descriptionmicrotubule associated protein 1 light chain 3 beta
- Target synonymsATG8F; autophagy-related ubiquitin-like modifier LC3 B; LC3B; MAP1 light chain 3-like protein 2; MAP1A/1BLC3; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1LC3B-a; microtubule-associated proteins 1A/1B light chain 3B
- HostRabbit
- IsotypeIgG
- Protein IDQ9GZQ8
- Protein NameMicrotubule-associated proteins 1A/1B light chain 3B
- Scientific DescriptionThe product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Phagocytic cell death leads to enhanced release of pro-inflammatory S100A12 in familial Mediterranean fever.Read more
- Modulation of autophagy, apoptosis and oxidative stress: a clue for repurposing metformin in photoaging.Read more
- Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT.Read more
- Docosahexaenoic acid promotes the formation of autophagosomes in MCF-7 breast cancer cells through oxidative stress-induced growth inhibitor 1 mediated activation of AMPK/mTOR pathway. Tsai CH et al., 2021 Aug, Food Chem ToxicolRead more
- Estrogen and estrogen receptors chauffeur the sex-biased autophagic action in liver. Mohapatra S et al., 2020 Nov, Cell Death DifferRead more
- Cell death induced autophagy contributes to terminal differentiation of skin and skin appendages. Koenig U et al., 2019 Aug 4, AutophagyRead more
- Tyrosinase-Cre-Mediated Deletion of the Autophagy Gene Atg7 Leads to Accumulation of the RPE65 Variant M450 in the Retinal Pigment Epithelium of C57BL/6 Mice. Sukseree S et al., 2016, PLoS OneRead more
- Autophagy facilitates secretion and protects against degeneration of the Harderian gland. Koenig U et al., 2015, AutophagyRead more
- Epidermal keratinocytes form a functional skin barrier in the absence of Atg7 dependent autophagy. Rossiter H et al., 2013 Jul, J Dermatol SciRead more
- Autophagy is induced by UVA and promotes removal of oxidized phospholipids and protein aggregates in epidermal keratinocytes. Zhao Y et al., 2013 Jun, J Invest DermatolRead more
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