WB analysis of arsenic trioxide treated U87-MG cell lysate using GTX82986 LC3B antibody.
WB analysis of arsenic trioxide treated U87-MG cell lysate using GTX82986 LC3B antibody.
LC3B antibody
GTX82986
ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Human, Mouse, Porcine, Primate, Rat, Zebra Fish
TargetMAP1LC3B
Overview
- SupplierGeneTex
- Product NameLC3B antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. ICC/IF: 0.1 - 2 microg/ml. IHC-P: 1:200 - 1:400. IHC-Fr: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsElectron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID81631
- Target nameMAP1LC3B
- Target descriptionmicrotubule associated protein 1 light chain 3 beta
- Target synonymsATG8F; autophagy-related ubiquitin-like modifier LC3 B; LC3B; MAP1 light chain 3-like protein 2; MAP1A/1BLC3; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1LC3B-a; microtubule-associated proteins 1A/1B light chain 3B
- HostRabbit
- IsotypeIgG
- Protein IDQ9GZQ8
- Protein NameMicrotubule-associated proteins 1A/1B light chain 3B
- Scientific DescriptionThe product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq]
- ReactivityBovine, Canine, Human, Mouse, Porcine, Primate, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Tyrosinase-Cre-Mediated Deletion of the Autophagy Gene Atg7 Leads to Accumulation of the RPE65 Variant M450 in the Retinal Pigment Epithelium of C57BL/6 Mice. Sukseree S et al., 2016, PLoS OneRead more
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- Autophagy is induced by UVA and promotes removal of oxidized phospholipids and protein aggregates in epidermal keratinocytes. Zhao Y et al., 2013 Jun, J Invest DermatolRead more