LC3B antibody [GT3612]
GTX632501
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMAP1LC3B
Overview
- SupplierGeneTex
- Product NameLC3B antibody [GT3612]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT3612
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID81631
- Target nameMAP1LC3B
- Target descriptionmicrotubule associated protein 1 light chain 3 beta
- Target synonymsATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a, microtubule-associated protein 1 light chain 3 beta, MAP1 light chain 3-like protein 2, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, autophagy-related ubiquitin-like modifier LC3 B, microtubule-associated proteins 1A/1B light chain 3B
- HostMouse
- IsotypeIgG2a
- Protein IDQ9GZQ8
- Protein NameMicrotubule-associated protein 1 light chain 3 beta
- Scientific DescriptionThe product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Zhang M, Yan W, Yu Y, et al. Liraglutide ameliorates diabetes-associated cognitive dysfunction via rescuing autophagic flux. J Pharmacol Sci. 2021,147(3):234-244. doi: 10.1016/j.jphs.2021.07.004Read this paper
- Wan C, Tai J, Zhang J, et al. Silver nanoparticles selectively induce human oncogenic γ-herpesvirus-related cancer cell death through reactivating viral lytic replication. Cell Death Dis. 2019,10(6):392. doi: 10.1038/s41419-019-1624-zRead this paper
- Tsai YG, Wen YS, Wang JY, et al. Complement regulatory protein CD46 induces autophagy against oxidative stress-mediated apoptosis in normal and asthmatic airway epithelium. Sci Rep. 2018,8(1):12973. doi: 10.1038/s41598-018-31317-5Read this paper



![ICC/IF analysis of PFA-fixed C6 cells with/without Chloroquine (50 microM, 37oC, 20 hrs) treatment using GTX00949 LC3B antibody [GT1187]. Right : untreated C6 cells Left : C6 cells with 50 microM Chloroquine (20 hrs, 37oC) treatment Orange : Primary antibody Blue : DAPI Dilution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX00949/GTX00949_20200327_ICC-IF_42_w_23053121_487.webp)

