LDHA antibody
GTX101416
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLDHA
Overview
- SupplierGeneTex
- Product NameLDHA antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.37 mg/ml
- ConjugateUnconjugated
- Gene ID3939
- Target nameLDHA
- Target descriptionlactate dehydrogenase A
- Target synonymscell proliferation-inducing gene 19 protein; epididymis secretory sperm binding protein Li 133P; GSD11; HEL-S-133P; lactate dehydrogenase M; LDH muscle subunit; LDH-A; LDHM; LDH-M; L-lactate dehydrogenase A chain; PIG19; proliferation-inducing gene 19; renal carcinoma antigen NY-REN-59
- HostRabbit
- IsotypeIgG
- Protein IDP00338
- Protein NameL-lactate dehydrogenase A chain
- Scientific DescriptionThe protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders. Baryla I et al., 2022 Mar 19, Int J Mol SciRead more
- Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1alpha/PDK1 Axis. Chen M et al., 2022, Oxid Med Cell LongevRead more
- Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells. Huang CY et al., 2021 Sep 14, Life (Basel)Read more
- Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2). Liang YC et al., 2021 Dec, Am J PatholRead more
- Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis. Hayashi K et al., 2021 Oct 1, Life SciRead more
- Characterization of TGF-beta by Induced Oxidative Stress in Human Trabecular Meshwork Cells. Chen HY et al., 2021 Jan 13, Antioxidants (Basel)Read more
- Biomarker discovery in highly invasive lung cancer cell through proteomics approaches. Kuo CH et al., 2021 Apr, Cell Biochem FunctRead more
- Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1alpha. Lee YZ et al., 2020 Feb, Pharmacol ResRead more
- CD36 inhibits beta-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis. Fang Y et al., 2019 Sep 4, Nat CommunRead more
- Proteomic analysis of evodiamine-induced cytotoxicity in thyroid cancer cells. Yu HI et al., 2018 Oct 25, J Pharm Biomed AnalRead more