LDHA antibody
GTX101416
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetLDHA
Overview
- SupplierGeneTex
- Product NameLDHA antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.37 mg/ml
- ConjugateUnconjugated
- Gene ID3939
- Target nameLDHA
- Target descriptionlactate dehydrogenase A
- Target synonymsGSD11, HEL-S-133P, LDHM, PIG19, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-A, LDH-M, cell proliferation-inducing gene 19 protein, epididymis secretory sperm binding protein Li 133P, lactate dehydrogenase M, proliferation-inducing gene 19, renal carcinoma antigen NY-REN-59
- HostRabbit
- IsotypeIgG
- Protein IDP00338
- Protein NameL-lactate dehydrogenase A chain
- Scientific DescriptionThe protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Baryła I, Styczeń-Binkowska E, Płuciennik E, et al. The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders. Int J Mol Sci. 2022,23(6). doi: 10.3390/ijms23063326Read this paper
- Chen M, Liu M, Luo Y, et al. Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1α/PDK1 Axis. Oxid Med Cell Longev. 2022,2022:7420507. doi: 10.1155/2022/7420507Read this paper
- Huang CY, Weng YT, Li PC, et al. Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells. Life (Basel). 2021,11(9). doi: 10.3390/life11090963Read this paper
- Liang YC, Su Q, Liu YJ, et al. Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2). Am J Pathol. 2021,191(12):2117-2132. doi: 10.1016/j.ajpath.2021.08.010Read this paper
- Hayashi K, Nakazato Y, Ouchi M, et al. Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis. Life Sci. 2021,282:119847. doi: 10.1016/j.lfs.2021.119847Read this paper
- Chen HY, Chou HC, Ho YJ, et al. Characterization of TGF-β by Induced Oxidative Stress in Human Trabecular Meshwork Cells. Antioxidants (Basel). 2021,10(1). doi: 10.3390/antiox10010107Read this paper
- Kuo CH, Lin MW, Hsu YW, et al. Biomarker discovery in highly invasive lung cancer cell through proteomics approaches. Cell Biochem Funct. 2021,39(3):367-379. doi: 10.1002/cbf.3599Read this paper
- Lee YZ, Guo HC, Zhao GH, et al. Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1α. Pharmacol Res. 2020,152:104581. doi: 10.1016/j.phrs.2019.104581Read this paper
- Fang Y, Shen ZY, Zhan YZ, et al. CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis. Nat Commun. 2019,10(1):3981. doi: 10.1038/s41467-019-11662-3Read this paper
- Yu HI, Chou HC, Su YC, et al. Proteomic analysis of evodiamine-induced cytotoxicity in thyroid cancer cells. J Pharm Biomed Anal. 2018,160:344-350. doi: 10.1016/j.jpba.2018.08.008Read this paper
Datasheet
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