Bio-Connect

LDHA antibody

GTX101416
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLDHA
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Overview

  • Supplier
    GeneTex
  • Product Name
    LDHA antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.37 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3939
  • Target name
    LDHA
  • Target description
    lactate dehydrogenase A
  • Target synonyms
    cell proliferation-inducing gene 19 protein; epididymis secretory sperm binding protein Li 133P; GSD11; HEL-S-133P; lactate dehydrogenase M; LDH muscle subunit; LDH-A; LDHM; LDH-M; L-lactate dehydrogenase A chain; PIG19; proliferation-inducing gene 19; renal carcinoma antigen NY-REN-59
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00338
  • Protein Name
    L-lactate dehydrogenase A chain
  • Scientific Description
    The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders. Baryla I et al., 2022 Mar 19, Int J Mol Sci
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  • Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1alpha/PDK1 Axis. Chen M et al., 2022, Oxid Med Cell Longev
    Read more
  • Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells. Huang CY et al., 2021 Sep 14, Life (Basel)
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  • Centromere Protein A (CENPA) Regulates Metabolic Reprogramming in the Colon Cancer Cells by Transcriptionally Activating Karyopherin Subunit Alpha 2 (KPNA2). Liang YC et al., 2021 Dec, Am J Pathol
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  • Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis. Hayashi K et al., 2021 Oct 1, Life Sci
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  • Characterization of TGF-beta by Induced Oxidative Stress in Human Trabecular Meshwork Cells. Chen HY et al., 2021 Jan 13, Antioxidants (Basel)
    Read more
  • Biomarker discovery in highly invasive lung cancer cell through proteomics approaches. Kuo CH et al., 2021 Apr, Cell Biochem Funct
    Read more
  • Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1alpha. Lee YZ et al., 2020 Feb, Pharmacol Res
    Read more
  • CD36 inhibits beta-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis. Fang Y et al., 2019 Sep 4, Nat Commun
    Read more
  • Proteomic analysis of evodiamine-induced cytotoxicity in thyroid cancer cells. Yu HI et al., 2018 Oct 25, J Pharm Biomed Anal
    Read more