
FACS analysis of HepG2 cells using GTX37639 LDL Receptor antibody.
LDL Receptor antibody
GTX37639
Overview
- SupplierGeneTex
- Product NameLDL Receptor antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID3949
- Target nameLDLR
- Target descriptionlow density lipoprotein receptor
- Target synonymsFH; FHC; FHCL1; LDL receptor; LDLCQ2; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3
- HostRabbit
- IsotypeIgG
- Protein IDP01130
- Protein NameLow-density lipoprotein receptor
- Scientific DescriptionThe low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chinese Olive (Canarium album L.) Fruit Extract Attenuates Metabolic Dysfunction in Diabetic Rats. Yeh YT et al., 2017 Oct 15, NutrientsRead more