LDLR Polyclonal Antibody

Reddot Biotech

LDLR Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

LDLR

low density lipoprotein receptor

FH; FHC; FHCL1; LDL receptor; LDLCQ2; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3

Rabbit

IgG

LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.

Human, Mouse, Rat

-20°C

12352203